Product thawing is the process of un-freezing Active Pharmaceutical Ingredient ready for Manufacturing and is usually one of the first steps in the manufacturing process. Products that require thawing are usually Cold chain products. I usually use a Frozen chicken simile to describe the process. There are two main ways to that a product, Forced Thaw and Passive Thaw. Products that are thawed typically have a minimum thaw time before being allowed to be used.