Heating Ventilation and Air Conditioning is a key part of facility cleanliness in Manufacturing, it is the same technology in place throughout industry for building management but with tighter requirements in temperature control (especially when dealing with Cold chain products), pressure/airflow control (for maintaining Pressure Cascades, and particulates.
HVAC requirements can change largely based on what grade of area is being supplied ranging from grade A isolator air to office spaces.
For particulate management typically a system of Bag Filters and HEPA filters are used to remove particulates from the air.
Pressure control and temperature control are typically controlled through a PID loop with area sensors to ensure they stay within control.
HVAC is commonly linked to a Building Management System or in a quality critical area a Environmental Monitoring System to manage excursions or issues.